Male Factor Studies

A prospective randomized placebo-controlled study of the effect of acupuncture in infertile patients with severe oligoasthenozoospermia
Dieterle et al Fertil Steril 2009 Oct; 92 (4): 1340–3 Fertility and Sterility CONCLUSION(S): This recent small clinical trial randomized 57 patients who had extremely low sperm counts, to acupuncture and placebo acupuncture groups. After receiving acupuncture twice weekly for 6 weeks motility of sperm (but not overall count) was found to increase significantly. The authors conclude that the results of the present study support the significance of acupuncture in male patients with severe oligoasthenozoospermia. More evidence with larger trials needs to be accumulated before the efficacy and effectiveness of acupuncture in male infertility can be evaluated.
Published on April 25, 2009

Antioxidant supplements and semen parameters: An evidence based review
Ahmadi S, Bashiri R, Ghadiri-Anari A, Nadjarzadeh A. 2016. Antioxidant supplements and semen parameters: An evidence based review. Int J Reprod Biomed. 14(12):729-736.
Published on December 14, 2016

Does acupuncture treatment affect sperm density in males with very low sperm count? A pilot study.
Siterman S, Eltes F, Wolfson V, Lederman H, Bartoov B., Andrologia. 2000 Jan;32(1):31-9. Source: Institute of Chinese Medicine, Tel Aviv, Israel. CONCLUSIONS: Acupuncture may be a useful, non-traumatic treatment for males with very poor sperm density, especially those with a history of genital tract inflammation.
Published on January 1, 2000

Does the Use of Mobile Phone Affect Male Fertility? A Mini-Review
Okechukwu CE. 2020. Does the Use of Mobile Phone Affect Male Fertility? A Mini-Review. J Hum Reprod Sci. 13(3):174-183.
Published on July 1, 2020

Effect of acupuncture on sperm parameters of males suffering from subfertility related to low sperm quality.
Siterman S, Eltes F, Wolfson V, Zabludovsky N, Bartoov B. Arch Androl. 1997 Sep-Oct;39(2):155-61. Source: Institute of Chinese Medicine, Tel Aviv, Israel. CONCLUSIONS: Patients exhibiting a low fertility potential due to reduced sperm activity may benefit from acupuncture treatment.
Published on October 1, 1997

Effects of acupuncture and moxa treatment in patients with semen abnormalities.
Edson Gurfinkel, Agnaldo P. Cedenho, Ysao Yamamura, Miguel Srougi – Human Reproduction Division, Discipline of Urology, São Paulo Federal University, Paulista School of Medicine, São Paulo, Brazil – Asian J Androl 2003 Dec; 5: 345-348 CONCLUSION(S): The Chinese Traditional Medicine acupuncture and moxa techniques significantly increase the percentage of normal-form sperm in patients with oligoastenoteratozoospermia without apparent cause.
Published on December 1, 2003

Green tea improves rat sperm quality and reduced cadmium chloride damage effect in spermatogenesis cycle
Mahmoudi R, Azizi A, Abedini S, Hemayatkhah Jahromi V, Abidi H, Jafari Barmak M. 2018. Green tea improves rat sperm quality and reduced cadmium chloride damage effect in spermatogenesis cycle. J Med Life. 11(4):371-380.
Published on October 14, 2018

Influence of oral vitamin and mineral supplementation on male infertility: a meta-analysis and systematic review
Buhling K, Schumacher A, Eulenburg CZ, Laakmann E. 2019. Influence of oral vitamin and mineral supplementation on male infertility: a meta-analysis and systematic review. Reprod Biomed Online. 39(2):269-279.
Published on August 15, 2019

Quantitative evaluation of spermatozoa ultrastructure after acupuncture treatment for idiopathic male infertility.
Pei J et al Fertil Steril. 2005 Jul;84(1):141-7 Fertility and Sterility CONCLUSION(S): The treatment of idiopathic male infertility could benefit from employing acupuncture. A general improvement of sperm quality, specifically in the ultrastructural integrity of spermatozoa, was seen after acupuncture, although we did not identify specific sperm pathologies that could be particularly sensitive to this therapy.
Published on July 1, 2005

Randomized, triple-blind, placebo-controlled clinical trial examining the effects of alpha-lipoic acid supplement on the spermatogram and seminal oxidative stress in infertile men
Haghighian HK, Haidari F, Mohammadi-Asl J, Dadfar M. 2015. Randomized, triple-blind, placebo-controlled clinical trial examining the effects of alpha-lipoic acid supplement on the spermatogram and seminal oxidative stress in infertile men. Fertil Steril. 104(2):318-24.
Published on August 1, 2015

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