Research

Methylenetetrahydrofolate reductase gene polymorphisms and recurrent pregnancy loss in China: a systematic review and meta-analysis
Chen H, Yang X, Lu M. 2016. Arch Gynecol Obstet. 293(2):283-90. Methylenetetrahydrofolate reductase gene polymorphisms and recurrent pregnancy loss in China: a systematic review and meta-analysis
Published on Feb 14, 2016

Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD+ redox
Yang L, Lin X, Tang H, et al. 2020. Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD+ redox. Aging Cell. 19(9):e13206.
Published on Sep 1, 2020

Moxibustion for Correction of Breech Presentation: A Randomized Controlled Trial
Francesco Cardini, MD; Huang Weixin, MD JAMA. 1998;280:1580-1584 CONCLUSION(S): Among primigravidas with breech presentation during the 33rd week of gestation, moxibustion for 1 to 2 weeks increased fetal activity during the treatment period and cephalic presentation after the treatment period and at delivery.
Published on Nov 11, 1998

N-Acetyl-Cysteine and l-Carnitine Prevent Meiotic Oocyte Damage Induced by Follicular Fluid From Infertile Women With Mild Endometriosis
Giorgi VS, Da Broi MG, Paz CC, Ferriani RA, Navarro PA. 2016. N-Acetyl-Cysteine and l-Carnitine Prevent Meiotic Oocyte Damage Induced by Follicular Fluid From Infertile Women With Mild Endometriosis. Reprod Sci. 23(3):342-51.
Published on Mar 1, 2016

NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
Yoshino J, Baur JA, Imai SI. 2018. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metab. 27(3):513-528.
Published on Mar 6, 2018

NAD+ Repletion Rescues Female Fertility during Reproductive Aging
Bertoldo MJ, Listijono DR, Ho WJ, et al. 2020. NAD+ Repletion Rescues Female Fertility during Reproductive Aging. Cell Rep. 30(6):1670-1681.e7.
Published on Feb 11, 2020

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice
Zhang H, Ryu D, Wu Y, Gariani K, Wang X, Luan P, D'Amico D, Ropelle ER, Lutolf MP, Aebersold R, Schoonjans K, Menzies KJ, Auwerx J. 2016. NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science. 352(6292):1436-43.
Published on Jun 17, 2016

Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes
Miao Y, Cui Z, Gao Q, Rui R, Xiong B. 2020. Nicotinamide Mononucleotide Supplementation Reverses the Declining Quality of Maternally Aged Oocytes. Cell Rep. 32(5):107987.
Published on Aug 4, 2020

Oral melatonin supplementation improves oocyte and embryo quality in women undergoing in vitro fertilization-embryo transfer
Nishihara T, Hashimoto S, Ito K, Nakaoka Y, Matsumoto K, Hosoi Y, Morimoto Y. 2014. Oral melatonin supplementation improves oocyte and embryo quality in women undergoing in vitro fertilization-embryo transfer. Gynecol Endocrinol. 30(5):359-62.
Published on May 1, 2014

Phthalate exposure and female reproductive and developmental outcomes: a systematic review of the human epidemiological evidence
Radke EG, Glenn BS, Braun JM, Cooper GS. 2019. Phthalate exposure and female reproductive and developmental outcomes: a systematic review of the human epidemiological evidence. Environ Int. 130:104580.
Published on Sep 1, 2019

Polymorphisms in the MTHFR gene influence embryo viability and the incidence of aneuploidy
Enciso M, Sarasa J, Xanthopoulou L, Bristow S, Bowles M, Fragouli E, Delhanty J, Wells D. 2016. Polymorphisms in the MTHFR gene influence embryo viability and the incidence of aneuploidy. Human Genetics. 135(5):555-568.
Published on May 1, 2016

Predicting the likelihood of live birth for elective oocyte cryopreservation: a counseling tool for physicians and patients
Goldman RH, Racowsky C, Farland LV, Munné S, Ribustello L, Fox JH. 2017. Predicting the likelihood of live birth for elective oocyte cryopreservation: a counseling tool for physicians and patients. Hum Reprod. 32(4):853-859.
Published on Apr 1, 2017

Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial
Xu, Y., Nisenblat, V., Lu, C., Li R., Qiao J., Zhen X., Wang S. 2018. Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial. Reprod Biol Endocrinol 16, 29.
Published on Mar 27, 2018

Pyrroloquinoline quinone (PQQ) supplementation during in vitro culture of murine embryos alters mitochondrial activity but has minimal effects on embryo development
Logsdon D.M., J.N. Knoche, W.B. Schoolcraft, R.L. Krisher. 2018. Pyrroloquinoline quinone (PQQ) supplementation during in vitro culture of murine embryos alters mitochondrial activity but has minimal effects on embryo development, POSTER SESSION, VOLUME 110, ISSUE 4, SUPPLEMENT, E169.
Published on Feb 19, 2021

Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells
Zhang J, Meruvu S, Bedi YS, Chau J, Arguelles A, Rucker R, Choudhury M. 2015. Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells. Nutr Res. 35(9):844-9.
Published on Dec 19, 2015

Pyrroloquinoline Quinone, a Redox-Active o-Quinone, Stimulates Mitochondrial Biogenesis by Activating the SIRT1/PGC-1α Signaling Pathway
Saihara K, Kamikubo R, Ikemoto K, Uchida K, Akagawa M. 2017. Pyrroloquinoline Quinone, a Redox-Active o-Quinone, Stimulates Mitochondrial Biogenesis by Activating the SIRT1/PGC-1α Signaling Pathway. Biochemistry. 56(50):6615-6625.
Published on Dec 19, 2017

Quantitative evaluation of spermatozoa ultrastructure after acupuncture treatment for idiopathic male infertility.
Pei J et al Fertil Steril. 2005 Jul;84(1):141-7 Fertility and Sterility CONCLUSION(S): The treatment of idiopathic male infertility could benefit from employing acupuncture. A general improvement of sperm quality, specifically in the ultrastructural integrity of spermatozoa, was seen after acupuncture, although we did not identify specific sperm pathologies that could be particularly sensitive to this therapy.
Published on Jul 1, 2005

Randomized non-invasive sham-controlled pilot trial of electroacupuncture for postpartum depression.
Chung KF, Yeung WF, Zhang ZJ, Yung KP, Man SC, Lee CP, Lam SK, Leung TW, Leung KY, Ziea ET, Taam Wong V., J Affect Disord. 2012 Dec 15;142(1-3):115-21. doi: 10.1016/j.jad.2012.04.008. Epub 2012 Jul 26. Source: Department of Psychiatry, University of Hong Kong, Hong Kong, SAR, China. kfchung@hkucc.hku.hk CONCLUSION: Both electroacupuncture and non-invasive sham acupuncture were effective for postpartum depression. Further studies utilizing larger sample size, better recruitment strategies, and home-based acupuncture treatment are warranted.
Published on Jul 26, 2012

Randomized, triple-blind, placebo-controlled clinical trial examining the effects of alpha-lipoic acid supplement on the spermatogram and seminal oxidative stress in infertile men
Haghighian HK, Haidari F, Mohammadi-Asl J, Dadfar M. 2015. Randomized, triple-blind, placebo-controlled clinical trial examining the effects of alpha-lipoic acid supplement on the spermatogram and seminal oxidative stress in infertile men. Fertil Steril. 104(2):318-24.
Published on Aug 1, 2015

Reduction of blood flow impedance in the uterine arteries of infertile women with electro-acupuncture.
Stener-Victorin E, Waldenström U, Andersson SA, Wikland M., Hum Reprod. 1996 Jun;11(6):1314-7. Source: Department of Obstetrics and Gynaecology, Fertility Centre Scandinavia, University of Gothenburg, S-413 45 Gothenburg, Sweden. CONCLUSION: Compared to the mean baseline PI (pulsatility index), the mean PI was significantly reduced both shortly after the eighth EA treatment (P < 0.0001) and 10-14 days after the EA period (P < 0.0001).
Published on Jun 11, 1996

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